Strand separation unravelled
نویسندگان
چکیده
منابع مشابه
Strand separation in negatively supercoiled DNA.
We consider Benham's model for strand separation in negatively supercoiled circular DNA, and study denaturation as function of the linking difference density kappa<0. We propose a statistical version of this model, based on bayesian segmentation methods of current use in bioinformatics; this leads to new algorithms with priors adapted to supercoiled DNA, taking into account the random nature of...
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ژورنال
عنوان ژورنال: Nature
سال: 2015
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature14643